Issued Patents All Time
Showing 25 most recent of 55 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12351839 | Rationally-designed single-chain meganucleases with non-palindromic recognition sequences | James Jefferson Smith | 2025-07-08 |
| 12338444 | Methods for producing a complex transgenic trait locus | Andrew Mark Cigan, Saverio Carl Falco, Huirong Gao, Michael Lassner, Zhongsen Li +3 more | 2025-06-24 |
| 12006522 | Polynucleotides encoding engineered meganucleases having specificity for recognition sequences in the dystrophin gene | Gary Owens, Janel Lape, James Jefferson Smith, John C. Morris, Caitlin Turner +1 more | 2024-06-11 |
| 11993793 | Polynucleotides encoding engineered meganucleases having specificity for recognition sequences in the dystrophin gene | Gary Owens, Janel Lape, James Jefferson Smith, John C. Morris, Caitlin Turner +1 more | 2024-05-28 |
| 11753630 | Polynucleotides encoding engineered meganucleases having specificity for recognition sequences in the dystrophin gene | Gary Owens, Janel Lape, James Jefferson Smith, John C. Morris, Caitlin Turner +1 more | 2023-09-12 |
| 11680254 | Engineered meganucleases specific for recognition sequences in the PCSK9 gene | Victor Bartsevich, James Jefferson Smith, Janel Lape | 2023-06-20 |
| 11459576 | Methods for producing a complex transgenic trait locus | Andrew Mark Cigan, Saverio Carl Falco, Huirong Gao, Michael Lassner, Zhongsen Li +3 more | 2022-10-04 |
| 11286291 | Co-stimulatory domains for use in genetically-modified cells | Aaron Martin, Jeffrey Sunman, Daniel T. MacLeod | 2022-03-29 |
| 11278632 | Engineered nucleases useful for treatment of hemophilia A | James Jefferson Smith, Victor Bartsevich, Clayton Beard, Michael G. Nicholson | 2022-03-22 |
| 11274285 | Engineered meganucleases specific for recognition sequences in the Hepatitis B virus genome | James Jefferson Smith | 2022-03-15 |
| 11266693 | Nucleic acids encoding engineered meganucleases with recognition sequences found in the human T cell receptor alpha constant region gene | Michael G. Nicholson, James Jefferson Smith, Victor Bartsevich, Daniel T. MacLeod, Jeyaraj Antony | 2022-03-08 |
| 11268065 | Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene | James Jefferson Smith, Michael G. Nicholson, Daniel T. MacLeod, Jeyaraj Antony, Victor Bartsevich | 2022-03-08 |
| 11053484 | Genetically-modified T cells comprising a modified intron in the T cell receptor alpha gene | James Jefferson Smith, Clayton Beard | 2021-07-06 |
| 10851358 | Engineered meganucleases specific for recognition sequences in the hepatitis B virus genome | James Jefferson Smith | 2020-12-01 |
| 10822610 | Methods for producing a complex transgenic trait locus | Andrew Mark Cigan, Saverio Carl Falco, Huirong Gao, Michael Lassner, Zhongsen Li +3 more | 2020-11-03 |
| 10800833 | Co-stimulatory domains for use in genetically-modified cells | Aaron Martin, Daniel T. MacLeod | 2020-10-13 |
| 10799535 | Engineered meganucleases with recognition sequences found in the human T cell receptor alpha constant region gene | Michael G. Nicholson, James Jefferson Smith, Victor Bartsevich, Daniel T. MacLeod, Jeyaraj Antony | 2020-10-13 |
| 10758595 | Treatment of retinitis pigmentosa using engineered meganucleases | Victor Bartsevich, James Jefferson Smith, Michael G. Nicholson | 2020-09-01 |
| 10745665 | Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof | Joann Hux, Aaron Martin, Clayton Beard | 2020-08-18 |
| 10662416 | Engineered meganucleases specific for recognition sequences in the hepatitis B virus genome | James Jefferson Smith | 2020-05-26 |
| 10662440 | Self-limiting viral vectors encoding nucleases | James Jefferson Smith, Michael G. Nicholson | 2020-05-26 |
| 10603363 | Treatment of retinitis pigmentosa using engineered meganucleases | Victor Bartsevich, James Jefferson Smith, Michael G. Nicholson | 2020-03-31 |
| 10287626 | Recognition sequences for I-CreI-derived meganucleases and uses thereof | James Jefferson Smith | 2019-05-14 |
| 10273524 | Recognition sequences for I-CreI-derived meganucleases and uses thereof | James Jefferson Smith | 2019-04-30 |
| 10093899 | Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene | James Jefferson Smith, Michael G. Nicholson, Daniel T. MacLeod, Jeyaraj Antony, Victor Bartsevich | 2018-10-09 |