| 11712480 |
Heteroaryl sulfone-based conjugation handles, methods for their preparation, and their use in synthesizing antibody drug conjugates |
Russell Dushin, Daniel Paul Uccello, Jeremy Tyson Starr, Ye Che, Mark E. Flanagan +8 more |
2023-08-01 |
$1,066,643,000 |
| 10391182 |
Bifunctional cytotoxic agents |
Andreas Maderna, Matthew David Doroski, Zecheng Chen, Hud Lawrence Risley, Jeffrey M. Casavant +2 more |
2019-08-27 |
$278,016,000 |
| 10086085 |
Bifunctional cytotoxic agents |
Andreas Maderna, Matthew David Doroski, Zecheng Chen, Hud Lawrence Risley, Jeffrey M. Casavant +2 more |
2018-10-02 |
$866,888,000 |
| 9764040 |
Spliceostatin analogs and methods for their preparation |
Chakrapani Subramanyam, Frank Koehn, Kenneth John Dirico, Alessandra S. Eustaquio, Michael Eric Green +6 more |
2017-09-19 |
$381,523,000 |
| 9751877 |
Substituted pyrido[1,2-a]pyrazines for the treatment of neurodegenerative and neurological disorders |
Martin Youngjin Pettersson, Douglas Scott Johnson, Chakrapani Subramanyam, Christopher William am Ende, Michael Eric Green +6 more |
2017-09-05 |
$172,618,000 |
| 9504669 |
Spliceostatin analogs and methods for their preparation |
Chakrapani Subramanyam, Frank Koehn, Kenneth John Dirico, Alessandra S. Eustaquio, Michael Eric Green +6 more |
2016-11-29 |
$771,469,000 |
| 9249186 |
Cytotoxic peptides and antibody drug conjugates thereof |
Matthew David Doroski, Andreas Maderna, Chakrapani Subramanyam, Beth Vetelino, Russell Dushin +2 more |
2016-02-02 |
$195,231,000 |
| 9193726 |
Substituted pyrido[1,2-a]pyrazines for the treatment of neurodegenerative and neurological disorders |
Martin Youngjin Pettersson, Douglas Scott Johnson, Chakrapani Subramanyam, Christopher William am Ende, Michael Eric Green +6 more |
2015-11-24 |
$383,549,000 |
| 9169264 |
Spliceostatin analogs and methods for their preparation |
Chakrapani Subramanyam, Frank Koehn, Kenneth John Dirico, Alessandra S. Eustaquio, Michael Eric Green +6 more |
2015-10-27 |
$660,560,000 |
| 9138486 |
Cytotoxic peptides and antibody drug conjugates thereof |
Matthew David Doroski, Andreas Maderna, Chakrapani Subramanyam, Beth Vetelino, Russell Dushin +2 more |
2015-09-22 |
$161,915,000 |
| 9067934 |
Bicyclic pyridinones |
Martin Youngjin Pettersson, Douglas Scott Johnson, Chakrapani Subramanyam, Christopher William am Ende, Benjamin Adam Fish +5 more |
2015-06-30 |
$178,322,000 |
| 8916564 |
Substituted pyrido[1,2-a]pyrazines for the treatment of neurodegenerative and neurological disorders |
Martin Youngjin Pettersson, Douglas Scott Johnson, Chakrapani Subramanyam, Christopher William am Ende, Michael Eric Green +6 more |
2014-12-23 |
$289,866,000 |
| 8828401 |
Cytotoxic peptides and antibody drug conjugates thereof |
Matthew David Doroski, Andreas Maderna, Chakrapani Subramanyam, Beth Vetelino, Russell Dushin +2 more |
2014-09-09 |
$296,433,000 |
| 8697673 |
Bicyclic pyridinones |
Martin Youngjin Pettersson, Douglas Scott Johnson, Chakrapani Subramanyam, Christopher William am Ende, Benjamin Adam Fish +5 more |
2014-04-15 |
$644,265,000 |
| 8686043 |
Heterocyclic sulfonamides, uses and pharmaceutical compositions thereof |
Anton Fliri, Randall J. Gallaschun, Jacob Bradley Schwarz, Barbara E. Segelstein |
2014-04-01 |
$235,129,000 |
| 8278457 |
Heterocyclic sulfonamides, uses and pharmaceutical compositions thereof |
Anton Fliri, Randall J. Gallaschun, Jacob Bradley Schwarz, Barbara E. Segelstein |
2012-10-02 |
$211,962,000 |
| 7456177 |
Heteroaryl fused azapolycyclic compounds |
Martin Patrick Allen, Jotham Wadsworth Coe, Spiros Liras, Brian Thomas O'Neill |
2008-11-25 |
$161,136,000 |
| 7442694 |
Diazabicyclic compounds useful in the treatment of CNS and other disorders |
Jotham Wadsworth Coe, Brian Thomas O'Neill, Lawrence Vincent |
2008-10-28 |
$154,383,000 |
| 7439236 |
Pharmaceutical composition for the treatment of CNS and other disorders |
Brian Thomas O'Neill, Jotham Wadsworth Coe |
2008-10-21 |
$218,522,000 |
| 6881734 |
Pharmaceutical composition for the treatment of CNS and other disorders |
Brian Thomas O'Neill, Jotham Wadsworth Coe |
2005-04-19 |
$1,054,965,000 |
| 6809094 |
Pharmaceutical composition for the treatment of CNS and other disorders |
Brian Thomas O'Neill, Jotham Wadsworth Coe |
2004-10-26 |
$279,762,000 |
| 6673811 |
1H-pyrrolo [3,2-b] pyridine-3-carboxylic acid amines as GABAA receptor ligands |
George D. Maynard, Manuka Ghosh |
2004-01-06 |
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