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DCN-1 modulating compounds and methods of use thereof |
Robert Nicewonger, Mauricio Cortes, Colin Diner, Ragy Haddad, Sriram Krishnamoorthy +7 more |
2025-11-18 |
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Modulators of DCN-1 and methods of use thereof |
Robert Nicewonger, Mauricio Cortes, Colin Diner, Sriram Krishnamoorthy, Naixi Li +6 more |
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N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides useful as CCR6 inhibitors |
Brian Stephen Gerstenberger, Andrew Christopher Flick, Daniel Wei-Shung Kung, Vincent Michael Lombardo, James John Mousseau +7 more |
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Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides |
Matthew Frank Brown, Agustin Casimiro-Garcia, Ye Che, Jotham Wadsworth Coe, Mark E. Flanagan +7 more |
2024-09-03 |
$1,055,482,000 |
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N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides useful as CCR6 inhibitors |
Brian Stephen Gerstenberger, Andrew Christopher Flick, Daniel Wei-Shung Kung, Vincent Michael Lombardo, James John Mousseau +7 more |
2023-07-25 |
$554,221,000 |
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Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides |
Matthew Frank Brown, Agustin Casimiro-Garcia, Ye Che, Jotham Wadsworth Coe, Mark E. Flanagan +7 more |
2021-09-07 |
$508,674,000 |
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N-substituted-dioxocyclobutenylamino-3-hydroxy-picolinamides useful as CCR6 inhibitors |
Brian Stephen Gerstenberger, Andrew Christopher Flick, Vincent Michael Lombardo, James John Mousseau, Philippe Marcel Nuhant +7 more |
2021-04-13 |
$1,297,023,000 |
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Bicyclic heteroaryl derivatives as CFTR potentiators |
Joseph Walter Strohbach, David Christopher Limburg, John Paul Mathias, John James Mousseau, Rajiah Aldrin Denny +2 more |
2020-09-08 |
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Pyrrolo[2,3-D]pyrimidinyl, pyrrolo[2,3-B]pyrazinyl, pyrrolo[2,3-B]pyridinyl acrylamides and epoxides thereof |
Matthew Frank Brown, Agustin Casimiro-Garcia, Ye Che, Mark E. Flanagan, Adam Matthew Gilbert +5 more |
2020-07-07 |
$1,138,994,000 |
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Pyrrolopyrimidines as CFTR potentiators |
Joseph Walter Strohbach, David Christopher Limburg, John Paul Mathias, Rajiah Aldrin Denny, Christoph Wolfgang Zapf +3 more |
2019-12-03 |
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Bicyclic heteroaryl derivatives as CFTR potentiators |
Joseph Walter Strohbach, David Christopher Limburg, John Paul Mathias, John James Mousseau, Rajiah Aldrin Denny +2 more |
2019-08-13 |
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Pyrrolopyrimidines as CFTR potentiators |
Joseph Walter Strohbach, David Christopher Limburg, John Paul Mathias, Rajiah Aldrin Denny, Christoph Wolfgang Zapf +3 more |
2019-05-28 |
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Bicyclic heteroaryl derivatives as CFTR potentiators |
Joseph Walter Strohbach, David Christopher Limburg, John Paul Mathias, John James Mousseau, Rajiah Aldrin Denny +2 more |
2019-02-19 |
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Bicyclic heteroaryl derivatives as CFTR potentiators |
Joseph Walter Strohbach, David Christopher Limburg, John Paul Mathias, John James Mousseau, Rajiah Aldrin Denny +2 more |
2018-11-20 |
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Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides |
Matthew Frank Brown, Agustin Casimiro-Garcia, Ye Che, Jotham Wadsworth Coe, Mark E. Flanagan +7 more |
2017-04-11 |
$241,476,000 |
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Macrocyclic compounds for modulating IL-17 |
Michael D. Taylor, Nicholas K. Terrett, William H. Connors, Cheri Snedeker, Kelley C. Shortsleeves +8 more |
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Heterocyclic compounds useful in treating diseases and conditions |
Tanisha D. Blake, Bruce C. Hamper, Wei Huang, James Richard Kiefer, Jr., Joseph B. Moon +6 more |
2011-11-29 |
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Nicotinamide derivatives |
Tanisha D. Blake, Bruce C. Hamper, Wei Huang, James Richard Kiefer, Jr., Joseph B. Moon +6 more |
2011-03-08 |
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Heterocyclic compounds useful in treating diseases and conditions |
Tanisha D. Blake, Bruce C. Hamper, Wei Huang, James Richard Kiefer, Jr., Joseph B. Moon +6 more |
2009-09-01 |
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4-thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carbothioamides as antiviral agents |
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2005-08-02 |
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Thioxazinoquinolones as antiviral agents |
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2004-11-23 |
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4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxamides as antiviral agents |
Valerie A. Vaillancourt |
2004-02-17 |
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Oxazinoquinolones useful for the treatment of viral infections |
Steven Ronald Turner, Suvit Thaisrivongs |
2004-01-06 |
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Heterocycle carboxamides as antiviral agents |
David Anderson, Gordon L. Bundy, Fred Lawrence Ciske, David R. Graber, Michael James Genin +8 more |
2003-09-23 |
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4-thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxamides as antiviral agents |
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2003-09-16 |
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