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Substituted 4-amino-5-benzoyl-2-(phenylamino)thiophene-3-carbonitriles and substituted 4-amino-5-benzoyl-2-(phenylamino)thiophene-3-carboxamides as tubulin polymerization inhibitors

US Patent 8410163 · Granted Apr 2, 2013

Estimated economic value: $243,000

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