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Process and intermediates for preparing 4'-trifluoromethylbiphenyl-2-carboxylic acid [2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-a mide

US Patent 5998623 · Granted Dec 7, 1999

Estimated economic value: $328,785,000

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