KR

Kenneth M. Ryan

Merck: 16 patents #667 of 9,382Top 8%
Overall (All Time): #280,690 of 4,157,543Top 7%
17
Patents All Time

Issued Patents All Time

Patent #TitleCo-InventorsDate
5489710 Regiospecific processes to make cis-1-amino-2-alkanol from diol Thomas R. Verhoeven, F. Edward Roberts, Chris Hugh Senanayake 1996-02-06
5449830 Regiospecific processes to make CIS-1-Amino-2-Alkanol from Diol or Halohydrin Thomas R. Verhoeven, Edward F. Roberts, Chris Hugh Senanayake 1995-09-12
5420353 Regiospecific process to make cis-1-amino-2-alkanol from epoxide Thomas R. Verhoeven, F. Edward Roberts, Christ H. Senanayake 1995-05-30
5087703 Process for synthesis of FK-506 intermediates Ralph P. Volante, David Askin, Ichiro Shinkai 1992-02-11
4499278 Trans-3-carboxymethylene-4-carboxy-5-methyl-delta2-isoxazoline as intermediate David G. Melillo 1985-02-12
4473502 Synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid Thomas M. H. Liu, David G. Melillo, Ichiro Shinkai, Meyer Sletzinger 1984-09-25
4467107 1-Hydroxyethyl-2-amino pentanedioic acid derivatives Thomas M. H. Liu, David G. Melillo, Ichiro Shinkai, Meyer Sletzinger 1984-08-21
4454332 Hydroxy amino dicarboxylic acids and esters Thomas M. H. Liu, David G. Melillo, Meyer Sletzinger, Ichiro Shinkai 1984-06-12
4414155 Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-.beta.,2-dioxo-4-azetidinebutanoic acid Thomas M. H. Liu, David G. Melillo, Ichiro Shinkai, Meyer Sletzinger 1983-11-08
4375433 Process for the preparation of 6-hydroxymethyl-2-(.beta.-aminoethylthio)-1-carbadethiapen-2-em-3-carbox ylic acid David G. Melillo 1983-03-01
4360684 Process for the preparation of (2S)-tetrahydro-2.alpha.-methyl-6-oxo-4.beta..alpha.-carboxylic acid Raymond Cvetovich, David G. Melillo, Meyer Sletzinger 1982-11-23
4349687 Intermediate for synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid Thomas M. H. Liu, David G. Melillo, Ichiro Shinkai, Meyer Sletzinger 1982-09-14
4344885 Intermediate for the preparation of thienamycin Thomas M. H. Liu, David G. Melillo, Ichiro Shinkai, Meyer Sletzinger 1982-08-17
4287123 Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate Thomas M. H. Liu, David G. Melillo, Ichiro Shinkai, Meyer Sletzinger 1981-09-01
4282148 Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-.beta.,2-dioxo-4-azetidinebutanoic acid Thomas M. H. Liu, David G. Melillo, Ichiro Shinkai, Meyer Sletzinger 1981-08-04
4269772 Synthesis of thienamycin via trans-3-carboxymethylene-4-carboxy-5-methyl-.DELTA..sup.2 -isoxazoline David G. Melillo 1981-05-26
4252722 Process for the preparation of 6-hydroxymethyl-2-(.beta.-aminoethylthio)-1-carbadethiapen-2-em-3-carbox ylic acid David G. Melillo 1981-02-24