HS

Harald Sobek

RO Roche Diagnostics Operations: 15 patents #49 of 1,692Top 3%
RG Roche Diagnostics Gmbh: 8 patents #13 of 851Top 2%
RS Roche Molecular Systems: 3 patents #149 of 746Top 20%
Overall (All Time): #157,917 of 4,157,543Top 4%
25
Patents All Time

Issued Patents All Time

Patent #TitleCo-InventorsDate
12234488 Mutant reverse transcriptase with increased thermal stability as well as products, methods and uses involving the same Christian Helmut Bell, Heiko Walch, Kiyoshi Yasukawa, Misato Baba 2025-02-25
11788108 CMP-dependent sialidase activity Michael Greif, Marco Thomann, Sebastian Malik 2023-10-17
11618892 Mutant reverse transcriptase with increased thermal stability as well as products, methods and uses involving the same Christian Helmut Bell, Heiko Walch, Kiyoshi Yasukawa, Misato Baba 2023-04-04
11078511 Aqueous composition Michael Greif, Marco Thomann, Sebastian Malik 2021-08-03
10227642 Detergent free polymerases Ulrike Fischer, Michael Greif, Johann-Peter Thalhofer 2019-03-12
9809835 Quantitative control of sialylation Alfred Engel, Michael Greif, Christine Jung, Sebastian Malik, Rainer Mueller +2 more 2017-11-07
9663769 T7 RNA polymerase variants with cysteine-serine substitutions Michael Greif, Christian Rudolph, Manfred Schmidt, Johann-Peter Thalhofer 2017-05-30
9631233 Dry composition of reaction compounds with stabilized polymerase Thomas Metzler, Tobias Haslinger, Annette Peceny 2017-04-25
9481902 Quantitative control of sialylation and specific mono-sialylation Tibor Czabany, Alfred Engel, Michael Greif, Christine Jung, Christiane Luley +9 more 2016-11-01
9193959 T7 RNA polymerase variants with enhanced thermostability Johann-Peter Thalhofer, Rainer Mueller, Manfred Schmidt, Michael Greif, Armin Ruf +1 more 2015-11-24
9163286 Dry composition of reaction compounds with stabilized polymerase Thomas Metzler, Tobias Haslinger, Annette Peceny 2015-10-20
8652811 Dry composition of reaction compounds with stabilized polymerase Thomas Metzler, Tobias Haslinger, Annette Peceny 2014-02-18
8476053 Stabilized aqueous alpha-galactosidase composition and methods relating thereto Manfred Schmidt, Rainer Mueller, Werner Hoelke, Johann-Peter Thalhofer 2013-07-02
7494797 Recombinant terminal deoxynucleotidyl transferase with improved functionality Rainer Mueller, Markus Pajatsch, Ingo Curdt, Manfred Schmidt, Bernhard Suppmann +2 more 2009-02-24
7429468 Mutant B-type DNA polymerases exhibiting improved performance in PCR Bruno Frey, Garabed Antranikian, Boehlke Kristina, Francesca Maria Pisani, Mose Rossi 2008-09-30
7410782 Thermostable enzyme promoting the fidelity of thermostable DNA polymerases—for improvement of nucleic acid synthesis and amplification in vitro Waltraud Ankenbauer, Frank Laue, Michael Greif 2008-08-12
7378262 Reversibly modified thermostable enzymes for DNA synthesis and amplification in vitro Michael Greif 2008-05-27
7244602 Polymerase chimeras Bruno Frey, Britta Villbrandt, Dietmar Schomburg, Waltraud Ankenbauer 2007-07-17
7030220 Thermostable enzyme promoting the fidelity of thermostable DNA polymerases-for improvement of nucleic acid synthesis and amplification in vitro Waltraud Ankenbauer, Frank Laue, Michael Greif 2006-04-18
6902920 Method for producing an active heterodimeric AMV-RT in prokaryotic cells Rainer Mueller, Manfred Schmidt, Bruno Frey, Bernhard Suppmann, Rainer Schmuck +3 more 2005-06-07
6881559 Mutant B-type DNA polymerases exhibiting improved performance in PCR Bruno Frey, Garabed Antranikian, Kristina Boehike, Francesca Maria Pisani, Mose Rossi 2005-04-19
6607883 Polymerase chimeras Bruno Frey, Britta Villbrandt, Dietmar Schomburg, Waltraud Ankenbauer 2003-08-19
6248522 Reduction of cross-contaminations in nucleic acid amplifications Gerd Haberhausen, Stephan Jager 2001-06-19
6187575 Thermolabile uracil-DNA-glycosylas, process for its preparation and use for removing uracil from DNA Manfred Schmidt, Bruno Frey, Klaus Kaluza 2001-02-13
6162633 Process and kit for fragment cloning Thomas Metzler, Rolf Reichhuber 2000-12-19