| 12043626 |
Solid forms, pharmaceutical compositions and preparation of heteroaromatic macrocyclic ether compounds |
Sibao Chen, Christopher G. F. COOPER, Joshua Courtney Horan, Jason Kropp, Benjamin S. Lane +1 more |
2024-07-23 |
$61,335,000 |
| 12037346 |
Amino-substituted heteroaryls for treating cancers with EGFR mutations |
Kristin L. Andrews, Joshua Courtney Horan, Scot Richard Mente, Henry Efrem Pelish, Matthew D. Shair +2 more |
2024-07-16 |
$60,574,000 |
| 11981687 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Richard A. Silva, Michael Louis Miller, Manami Shizuka |
2024-05-14 |
|
| 11926619 |
Certain pladienolide compounds and methods of use |
Gregg F. Keaney, John Wang, Kenzo Arai, Xiang LIU, Guo Zhu Zheng +20 more |
2024-03-12 |
|
| 11760759 |
Process for preparing substituted indolines |
Richard A. Silva, Michael Louis Miller, Manami Shizuka |
2023-09-19 |
$139,479,000 |
| 11420982 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Manami Shizuka, Michael Louis Miller, Richard A. Silva |
2022-08-23 |
$21,551,000 |
| 11390633 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Richard A. Silva, Michael Louis Miller, Manami Shizuka |
2022-07-19 |
$17,202,000 |
| 10975099 |
Thiophene compounds for long-acting injectable compositions and related methods |
Brian M. Aquila, Hoan Huynh, Lewis D. Pennington, Ingo Andreas Mugge, Markus Haeberlein +5 more |
2021-04-13 |
|
| 10968228 |
Methods of preparing substituted 12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indoles |
Richard A. Silva, Michael Louis Miller, Manami Shizuka |
2021-04-06 |
$27,941,000 |
| 10899775 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Manami Shizuka, Michael Louis Miller, Richard A. Silva |
2021-01-26 |
$13,807,000 |
| 10844078 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Richard A. Silva, Michael Louis Miller, Manami Shizuka |
2020-11-24 |
$10,083,000 |
| 10807995 |
Thienothiophene compounds for long-acting injectable compositions and related methods |
Brian M. Aquila, Hoan Huynh, Lewis D. Pennington, Ingo Andreas Mugge, Markus Haeberlein +5 more |
2020-10-20 |
|
| 10799496 |
Naphthylenyl compounds for long-acting injectable compositions and related methods |
Brian M. Aquila, Hoan Huynh, Lewis D. Pennington, Ingo Andreas Mugge, Markus Haeberlein +5 more |
2020-10-13 |
|
| 10787463 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Manami Shizuka, Michael Louis Miller, Richard A. Silva |
2020-09-29 |
$13,704,000 |
| 10745387 |
Crystalline form of (2S,3S,6S,7R,10R,E)-7,10-dihydroxy-3,7-dimethyl-12-oxo-2-((R,2E,4E)-6-(piridin-2-yl)hepta-2,4-dien-2-yl)oxacyclododec-4-en-6-yl-4-methylpiperazine-1-carboxylate and methods of use thereof |
Gregg F. Keaney, John Wang, Kenzo Arai, Xiang LIU, Guo Zhu Zheng +19 more |
2020-08-18 |
|
| 10442809 |
Methods for preparing substituted 12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-ones |
Richard A. Silva, Michael Louis Miller, Manami Shizuka |
2019-10-15 |
$3,951,000 |
| 10392407 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Manami Shizuka, Michael Louis Miller, Richard A. Silva |
2019-08-27 |
$8,575,000 |
| 10385071 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Richard A. Silva, Michael Louis Miller, Manami Shizuka |
2019-08-20 |
$8,897,000 |
| 10370389 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Manami Shizuka, Michael Louis Miller, Richard A. Silva |
2019-08-06 |
$8,682,000 |
| 10081640 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Manami Shizuka, Michael Louis Miller, Richard A. Silva |
2018-09-25 |
$21,327,000 |
| 9890179 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Manami Shizuka, Michael Louis Miller, Richard A. Silva |
2018-02-13 |
$27,061,000 |
| 9873708 |
Methods of preparing cytotoxic benzodiazepine derivatives |
Manami Shizuka, Michael Louis Miller, Richard A. Silva |
2018-01-23 |
$21,250,000 |
| 9481669 |
Pladienolide pyridine compounds and methods of use |
Gregg F. Keaney, John Wang, Kenzo Arai, Xiang LIU, Guo Zhu Zheng +17 more |
2016-11-01 |
|
| 8404088 |
Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral bronsted acids |
John A. Porco, Jr. |
2013-03-26 |
|
| 8137509 |
Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral brønsted acids |
John A. Porco, Jr. |
2012-03-20 |
|