Issued Patents All Time
Showing 51–75 of 77 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 8349332 | Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases | Chien-Hsing Chang, David M. Goldenberg | 2013-01-08 |
| 8333971 | Methods and compositions for treatment of human immunodeficiency virus infection with conjugated antibodies or antibody fragments | David M. Goldenberg, Chien-Hsing Chang, William J. McBride | 2012-12-18 |
| 8282934 | Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology | Chien-Hsing Chang, David M. Goldenberg | 2012-10-09 |
| 8277817 | PEGylation by the dock and lock (DNL) technique | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2012-10-02 |
| 8246960 | Methods and compositions for generating bioactive assemblies of increased complexity and uses | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2012-08-21 |
| 8211440 | Multivalent immunoglobulin-based bioactive assemblies | Chien-Hsing Chang, David M. Goldenberg | 2012-07-03 |
| 8192739 | Fusion proteins containing recombinant cytotoxic RNAses | David M. Goldenberg, Hans J. Hansen, Chien-Hsing Chang, Sailaja S. Vanama | 2012-06-05 |
| 8163291 | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2012-04-24 |
| 8158129 | Dimeric alpha interferon PEGylated site-specifically shows enhanced and prolonged efficacy in vivo | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2012-04-17 |
| 8153433 | Mammalian cell lines for increasing longevity and protein yield from a cell culture | David M. Goldenberg, Zhengxing Qu, Chien-Hsing Chang, Jeng-Dar Yang, Diane Nordstrom | 2012-04-10 |
| 8076140 | Mammalian cell lines for increasing longevity and protein yield from a cell culture | David M. Goldenberg, Zhengxing Qu, Chien-Hsing Chang, Jeng-Dar Yang, Diane Nordstrom | 2011-12-13 |
| 8034352 | Tetrameric cytokines with improved biological activity | Chien-Hsing Chang, David M. Goldenberg | 2011-10-11 |
| 8003111 | Dimeric alpha interferon pegylated site-specifically shows enhanced and prolonged efficacy in vivo | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2011-08-23 |
| 7981398 | PEGylation by the dock and lock (DNL) technique | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2011-07-19 |
| 7906121 | Methods and compositions for generating bioactive assemblies of increased complexity and uses | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2011-03-15 |
| 7906118 | Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology | Chien-Hsing Chang, David M. Goldenberg | 2011-03-15 |
| 7871622 | Stably tethered structures of defined compositions with multiple functions or binding specificities | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2011-01-18 |
| 7858070 | Multivalent immunoglobulin-based bioactive assemblies | Chien-Hsing Chang, David M. Goldenberg | 2010-12-28 |
| 7785880 | Mammalian cell lines for increasing longevity and protein yield from cell culture | David M. Goldenberg, Zhengxing Qu, Chien-Hsing Chang, Jeng-Dar Yang, Diane Nordstrom | 2010-08-31 |
| 7666400 | PEGylation by the dock and lock (DNL) technique | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2010-02-23 |
| 7550143 | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2009-06-23 |
| 7544487 | Fusion proteins containing recombinant cytotoxic RNAses | David M. Goldenberg, Hans J. Hansen, Chien-Hsing Chang, Sailaja S. Vanama | 2009-06-09 |
| 7537930 | Mammalian cell lines for increasing longevity and protein yield from a cell culture | David M. Goldenberg, Zhengxing Qu, Chien-Hsing Chang, Jeng-Dar Yang, Diane Nordstrom | 2009-05-26 |
| 7534866 | Methods and compositions for generating bioactive assemblies of increased complexity and uses | Chien-Hsing Chang, David M. Goldenberg, William J. McBride | 2009-05-19 |
| 7531327 | Methods and compositions for increasing longevity and protein yield from a cell culture | David M. Goldenberg, Zhengxing Qu, Eva M. Horak, Ivan David Horak, Chien-Hsing Chang +1 more | 2009-05-12 |