Issued Patents All Time
Showing 51–75 of 76 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 5801038 | Modified subtilisins having amino acid alterations | Richard R. Bott, Robert M. Caldwell, Brian C. Cunningham, David A. Estell, Scott D. Power | 1998-09-01 |
| 5780279 | Method of selection of proteolytic cleavage sites by directed evolution and phagemid display | David Matthews, Mark Zoller | 1998-07-14 |
| 5780285 | Subtilisin variants capable of cleaving substrates containing dibasic residues | Marcus Ballinger | 1998-07-14 |
| 5763256 | Serine protease variants having peptide ligase activity | Lars Abrahmsen, John Burnier | 1998-06-09 |
| 5763257 | Modified subtilisins having amino acid alterations | Richard R. Bott, Robert M. Caldwell, Brian C. Cunningham, David A. Estell, Scott D. Power | 1998-06-09 |
| 5750373 | Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants | Lisa J. Garrard, Dennis J. Henner, Steven H. Bass, Ronald Greene, Henry B. Lowman +1 more | 1998-05-12 |
| 5741664 | Subtilisin variants capable of cleaving substrates containing dibasic residues | Marcus Ballinger | 1998-04-21 |
| 5736512 | Serine protease variants having peptide ligase activity | Lars Abrahmsen, John Burnier, David T. Jackson | 1998-04-07 |
| 5700676 | Modified subtilisins having amino acid alterations | Richard R. Bott, Robert M. Caldwell, Brian C. Cunningham, David A. Estell, Scott D. Power | 1997-12-23 |
| 5688666 | Growth hormone variants with altered binding properties | Steven H. Bass, Ronald Greene, Henry B. Lowman | 1997-11-18 |
| 5652136 | Substrate assisted catalysis | Paul Carter | 1997-07-29 |
| 5629173 | Methods of use of serine protease variants having peptide ligase activity | Lars Abrahmsen, John Burnier, David Y. Jackson | 1997-05-13 |
| 5580723 | Method for identifying active domains and amino acid residues in polypeptides and hormone variants | Brian C. Cunningham | 1996-12-03 |
| 5534617 | Human growth hormone variants having greater affinity for human growth hormone receptor at site 1 | Brian C. Cunningham, Henry B. Lowman | 1996-07-09 |
| 5506107 | Selecting ligand agonists and antagonists | Brian C. Cunningham, Abraham M. DeVos, Michael George Mulkerrin, Mark Ultsch | 1996-04-09 |
| 5472855 | Substrate assisted catalysis | Paul Carter | 1995-12-05 |
| 5441882 | Method for preparing modified subtilisins | David A. Estell, Richard R. Bott | 1995-08-15 |
| 5411873 | Process for producing heterologous polypeptides | Robin M. Adams, Scott D. Power, David Powers, Daniel Yansura | 1995-05-02 |
| 5403737 | Serine protease variants having peptide ligase activity | Lars Abrahmsen, John Burnier | 1995-04-04 |
| 5371190 | Substrate assisted catalysis | Paul Carter | 1994-12-06 |
| 5371008 | Substrate assisted catalysis | Paul Carter | 1994-12-06 |
| 5346823 | Subtilisin modifications to enhance oxidative stability | David A. Estell, Richard R. Bott | 1994-09-13 |
| RE34606 | Modified enzymes and methods for making same | David A. Estell, Richard R. Bott | 1994-05-10 |
| 5310675 | Procaryotic carbonyl hydrolases | David A. Estell, Eugenio Ferrari, Dennis J. Henner | 1994-05-10 |
| 5182204 | Non-human carbonyl hydrolase mutants, vectors encoding same and hosts transformed with said vectors | David A. Estell, Richard R. Bott, Scott D. Power | 1993-01-26 |