Patent Leaderboard
USPTO Patent Rankings Data through Dec 31, 2025
LS

Lyle W. Spruce — 36 Patents

COCortech: 27 patents #1 of 29Top 4%
IDIncyte San Diego: 6 patents #4 of 14Top 30%
OPOrtho-Mcneil Pharmaceutical: 4 patents #95 of 449Top 25%
MPMaxim Pharmaceuticals: 1 patents #10 of 22Top 50%
Stillwater, OK: #4 of 455 inventorsTop 1%
Oklahoma: #155 of 12,736 inventorsTop 2%
Overall (All Time): #92,222 of 4,157,543Top 3%
36 Patents All Time
Lyle W. Spruce has been granted 36 US patents while listed as an inventor at Cortech. The first was granted in 1989 and the most recent in June 2007. Lyle W. Spruce ranks #92,222 of 4,157,543 US inventors in our database (top 2.2%). Patent records list Lyle W. Spruce in Stillwater, OK, US.

Issued Patents All Time

Showing 1–25 of 36 patents

Patent #TitleCo-InventorsDateApprox Value ⓘ
7226940 Substituted heterocycles for the treatment of diabetes and other diseases Magnus Pfahl, Catherine Tachdjian, Hussien Al-Shamma, Andrea Fanjul, David Pleynet 2007-06-05 $5,195,000
7196108 Bicyclic heterocycles for the treatment of diabetes and other diseases Magnus Pfahl, Catherine Tachdjian, Hussien Al-Shamma, Andrea Giachino, Karine Jakubowicz-Jaillardon +3 more 2007-03-27 $3,702,000
7153875 Heterocyclic derivatives for the treatment of cancer and other proliferative diseases Magnus Pfahl, Catherine Tachdjian, Hussien Al-Shamma, Andrea Fanjul, David Pleynet +2 more 2006-12-26 $6,353,000
7071218 N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders; cancer, and other diseases Magnus Pfahl, Catherine Tachdjian, Hussien Al-Shamma, Mohamed Boudjelal, Andrea Fanjul +2 more 2006-07-04
6974826 Imidazolidinedione derivatives for the treatment of diabetes and other diseases Magnus Pfahl, Catherine Tachdjian, Hussien Al-Shamma, Andrea Fanjul, David Pleynet 2005-12-13 $7,350,000
6765013 Thiazolidinedione derivatives for the treatment of diabetes and other diseases Magnus Pfahl, Catherine Tachdjian, Hussien Al-Shamma, Andrea Fanjul, David Pleynet 2004-07-20 $7,485,000
6656910 Serine protease inhibitors Albert Gyorkos 2003-12-02 $82,000
6656911 Serine protease inhibitors Albert Gyorkos 2003-12-02 $82,000
6608175 Serine protease inhibitors Albert Gyorkos 2003-08-19 $170,000
6548638 Peptoid and nonpeptoid containing &agr;-keto oxadiazoles as serine protease inhibitors Albert Gyorkos, Kazuyuki Ohmoto, Kazuhito Kawabata 2003-04-15 $155,000
6515003 Heterocyclic derivatives for the treatment of diabetes and other diseases Magnus Pfahl, Catherine Tachdjian, Hussien Al-Shamma, Andrea Fanjul, David Pleynet 2003-02-04 $1,149,000
6255453 Peptoid and nonpeptoid containing alpha-keto oxadiazoles as serine protease inhibitors Albert Gyorkos, Kazuyuki Ohmoto, Kazuhito Kawabata 2001-07-03 $297,000
6159938 Serine protease inhibitors comprising .alpha.-keto heterocycles Albert Gyorkos, Axel Leimer, John C. Cheronis 2000-12-12 $365,000
6150334 Serine protease inhibitors-tripeptoid analogs Albert Gyorkos 2000-11-21 $343,000
6100238 Indole and tetrahydroisoquinoline containing Alpha-keto oxadiazoles as serine protease inhibitors Albert Gyorkos 2000-08-08 $239,000
6075120 Bradykinin antagonist John C. Cheronis, James K. Blodgett, Val S. Goodfellow, Manoj Vinayak Marathe, Eric T. Whalley 2000-06-13 $272,000
6037325 Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase Albert Gyorkos 2000-03-14 $254,000
6015791 Serine protease inhibitors-cycloheptane derivatives Albert Gyorkos 2000-01-18 $123,000
6004933 Cysteine protease inhibitors Albert Gyorkos, John C. Cheronis, Val S. Goodfellow, Axel Leimer, John M. Young +1 more 1999-12-21 $120,000
6001811 Serine protease inhibitors--N-substituted derivatives Albert Gyorkos 1999-12-14 $42,000
6001814 Serine protease inhibitors Albert Gyorkos 1999-12-14 $42,000
6001813 Val-pro containing .alpha.-keto oxadiazoles as serine protease inhibitors Albert Gyorkos 1999-12-14 $42,000
5998379 Serine protease inhibitors-proline analogs Albert Gyorkos 1999-12-07 $115,000
5891852 Serine protease inhibitors-cycloheptane derivatives Albert Gyorkos 1999-04-06 $201,000
5874585 Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase Albert Gyorkos 1999-02-23 $301,000