Patent Leaderboard
USPTO Patent Rankings Data through Dec 31, 2025
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Robert Osborne — 24 Patents

COCodexis: 20 patents #40 of 250Top 20%
ISInvista North America S.A.R.L.: 2 patents #107 of 403Top 30%
EAE.I. Du Pont De Nemours And: 2 patents #5,106 of 12,129Top 45%
Raleigh, NC: #303 of 6,378 inventorsTop 5%
North Carolina: #1,791 of 45,564 inventorsTop 4%
Overall (All Time): #168,038 of 4,157,543Top 5%
24 Patents All Time
Robert Osborne has been granted 24 US patents while listed as an inventor at Codexis. The first was granted in 1989 and the most recent in July 2025. Robert Osborne ranks #168,038 of 4,157,543 US inventors in our database (top 4.0%). Patent records list Robert Osborne in Raleigh, NC, US.

Issued Patents All Time

Showing 1–24 of 24 patents

Patent #TitleCo-InventorsDateApprox Value ⓘ
12365882 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2025-07-22
12286648 Engineered proline hydroxylase biocatalysts for hydroxylation of chemical compounds Jovana Nazor, Jack Liang, Jonathan Vroom, Xiyun Zhang, David Entwistle +6 more 2025-04-29
11807874 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2023-11-07 $2,089,000
11634695 Vectors for expression of biocatalysts Jovana Nazor, Jack Liang, Jonathan Vroom, Xiyun Zhang, David Entwistle +6 more 2023-04-25 $5,225,000
11591578 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2023-02-28 $3,058,000
11279917 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2022-03-22 $9,225,000
10982197 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2021-04-20 $10,484,000
10844358 Polynucleotides encoding biocatalysts and methods for hydroxylation of chemical compounds Jovana Nazor, Jack Liang, Jonathan Vroom, Xiyun Zhang, David Entwistle +6 more 2020-11-24 $12,211,000
10704030 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2020-07-07 $8,176,000
10689627 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2020-06-23 $7,776,000
10450550 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2019-10-22 $7,208,000
10273229 N-substituted 4-aminoquinazoline derivatives and methods of use Gjalt W. Huisman, Jed Hubbs, Xiyun Zhang 2019-04-30 $11,382,000
10184117 Biocatalysts and methods for hydroxylation of chemical compounds Jovana Nazor, Jack Liang, Jonathan Vroom, Xiyun Zhang, David Entwistle +6 more 2019-01-22 $10,924,000
10113153 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2018-10-30 $9,829,000
10100289 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2018-10-16 $3,342,000
10045987 Imidazoyl anilide derivatives and methods of use Gjalt W. Huisman, Jed Hubbs, Xiyun Zhang 2018-08-14 $4,751,000
9708587 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2017-07-18 $1,365,000
9683220 P450-BM3 variants with improved activity Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore 2017-06-20 $1,276,000
9670493 Low-phosphate repressible promoter Fernando Valle, Patricia Choudhary, Saul Nitsche Rocha, Monica Bhatia, U Loi Lao +1 more 2017-06-06 $2,303,000
9512447 Modified native beta-ketoacyl-ACP synthases and engineered microorganisms Smita Shankar, Louis Clark, Jonathan Vroom, Fernando Valle, Catherine M. Cho 2016-12-06 $719,000
9040754 Product recovery process in the filtration of polyether polyols Willard L. Quon 2015-05-26
8809491 Depolymerization of oligomeric cyclic ethers Paul S. Pearlman, Yanhui Sun 2014-08-19
5284980 Block copolyethers via oxonium coupling of poly(tetramethylene ether) glycols Gerfried Pruckmayr 1994-02-08 $15,849,000
4874884 Promoter synergism in pentenenitrile hydrocyanation Ronald J. McKinney 1989-10-17 $11,618,000