| RE50594 |
Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors |
Andreas Gollner, Joachim BROEKER, Nina Kerres, Christiane Kofink, Juergen Ramharter +4 more |
2025-09-23 |
| 11053237 |
Process for the manufacture of 6-alkynyl-pyridine derivatives |
Guanghua Lu, Thomas Krueger, Michael Pangerl, Marco Santagostino, Jean-Nicolas Desrosiers |
2021-07-06 |
| 10882866 |
Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors |
Andreas Gollner, Joachim BROEKER, Nina Kerres, Christiane Kofink, Juergen Ramharter +4 more |
2021-01-05 |
| 10717742 |
Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors |
Andreas Gollner, Joachim BROEKER, Nina Kerres, Christiane Kofink, Juergen Ramharter +4 more |
2020-07-21 |
| 8993753 |
Stereoselective synthesis of bicyclic heterocycles |
Markus Ostermeier, Juergen Daeubler, Stephan Kling, Marco Santagostino |
2015-03-31 |
| 8906931 |
9-[4-(3-chloro-2-fluoro-phenylamino-7-methoxy-quinazoline-6-yloxy]-1,4-diaza-spiro[5.5]undecane-5-one dimaleate, use thereof as a medicament and method for the production thereof |
Waldemar Pfrengle, Markus Ostermeier, Peter Sieger |
2014-12-09 |
| 8853225 |
9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy-quinazoline-6-yloxy]-1,4-diaza-spiro[5.5] undecane-5-one dimaleate, use thereof as a medicament and method for the production thereof |
Waldermar Pfrengle, Markus Ostermeier, Peter Sieger |
2014-10-07 |
| 8658790 |
Stereoselective synthesis of bicyclic heterocycles |
Markus Ostermeier, Juergen Daeubler, Stephan Kling, Marco Santagostino |
2014-02-25 |
| 8263768 |
Process for the stereoselective preparation of bicyclic heterocycles |
Markus Ostermeier, Stefan Braith, Juergen Daeubler, Waldemar Pfrengle |
2012-09-11 |
| 8222402 |
Preparation process |
Kathrin Pachur, Stefan Goepper, Michael Konrad, Kathrin Maier, Werner Rall +2 more |
2012-07-17 |
| 8119797 |
Production method |
Werner Rall, Uwe Reis |
2012-02-21 |
| 8084634 |
Production method |
Werner Rall, Uwe Reis |
2011-12-27 |
| 7696346 |
Production method |
Werner Rall, Uwe Ries |
2010-04-13 |
| 7638625 |
Crystalline compounds |
Uwe Ries, Sonja Sproll, Ulrike Werthmann, Andreas Zopf |
2009-12-29 |