Issued Patents All Time
Showing 25 most recent of 58 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12187759 | TLR7 agonists | James Appleman | 2025-01-07 |
| 12037335 | Substituted purines as TLR7 agonists | James Appleman | 2024-07-16 |
| 11952375 | Crystalline forms of Mnk inhibitors | Siegfried H. Reich, Paul A. Sprengeler, Alan X. Xiang, Justin T. Ernst, Bennett C. Borer +2 more | 2024-04-09 |
| 11692005 | TLR7 agonists | James Appleman | 2023-07-04 |
| 11130757 | Crystalline forms of MNK inhibitors | Siegfried H. Reich, Paul A. Sprengeler, Alan X. Xiang, Justin T. Ernst, Bennett C. Borer +2 more | 2021-09-28 |
| 11059824 | Substituted purines as TLR7 agonists | James Appleman | 2021-07-13 |
| 11014926 | Pyrrolo-, pyrazolo-, imidazo-pyrimidine and pyridine compounds that inhibit MNK1 and MNK2 | Paul A. Sprengeler, Siegfried H. Reich, Justin T. Ernst | 2021-05-25 |
| 10711008 | Indoline analogs and uses thereof | — | 2020-07-14 |
| 10351569 | Indoline analogs and uses thereof | — | 2019-07-16 |
| 10227344 | CK2 inhibitors, compositions and methods thereof | Xueliang Tao, Elena Brin | 2019-03-12 |
| 10112955 | Isoindoline, azaisoindoline, dihydroindenone and dihydroazaindenone inhibitors of Mnk1 and Mnk2 | Paul A. Sprengeler, Siegfried H. Reich, Justin T. Ernst, Mike Shaghafi, Douglas E. Murphy +1 more | 2018-10-30 |
| 10000487 | Heterocyclic compounds that inhibit the kinase activity of Mnk useful for treating various cancers | Paul A. Sprengeler, Seigfried H. Reich, Justin T. Ernst | 2018-06-19 |
| 9822122 | Indoline analogs and uses thereof | — | 2017-11-21 |
| 9814718 | MNK inhibitors and methods related thereto | Siegfried H. Reich, Paul A. Sprengeler, Alan X. Xiang, Justin T. Ernst | 2017-11-14 |
| 9669031 | MNK inhibitors and methods related thereto | Siegfried H. Reich, Paul A. Sprengeler, Alan X. Xiang, Justin T. Ernst | 2017-06-06 |
| 9382248 | Mnk inhibitors and methods related thereto | Siegfried H. Reich, Paul A. Sprengeler, Alan X. Xiang, Justin T. Ernst | 2016-07-05 |
| 8883758 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | Gregory J. Haley, Joseph R. Lennox, Alan X. Xiang, Erik J. Rueden | 2014-11-11 |
| 8586578 | Deuterated 5,6-dihydro-1H-pyridin-2-one compounds | — | 2013-11-19 |
| 8129368 | 5,6-dihydro-1H-pyridin-2-one compounds | Frank Ruebsam, Chinh Viet Tran, Douglas E. Murphy, Peggy A. Thompson, Peter Dragovich | 2012-03-06 |
| 8097718 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | Gregory J. Haley, Joseph R. Lennox, Alan X. Xiang, Erik J. Rueden | 2012-01-17 |
| 8097613 | [1,2,4]thiadiazine 1,1-dioxide compounds | Frank Ruebsam, Peter Dragovich, Douglas E. Murphy, Chinh Viet Tran | 2012-01-17 |
| 7964724 | Chiral cis-imidazolines | Nader Fotouhi, Gregory J. Haley, Klaus Baek Simonsen, Binh Thanh Vu | 2011-06-21 |
| 7943759 | 3-β-D-ribofuranosylthiazolo[4-5-d]pyrimidine nucleosides and uses thereof | Devron R. Averett, Joseph R. Lennox, Erik J. Rueden, David Louis Clark, Alan X. Xiang | 2011-05-17 |
| 7842838 | Pyrro[1,2-b]pyridazinone intermediates | Frank Ruebsam, Martin Tran, Peter Dragovich, Liansheng Li, Douglas E. Murphy +3 more | 2010-11-30 |
| 7781581 | Process for the preparation of 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-one | Tingman Wang, John S. Ng | 2010-08-24 |