Issued Patents All Time
Showing 25 most recent of 63 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12421274 | Polymer beads for oligonucleotide synthesis | Logan Garner, John Davies, Thomas Jacob Cobb, Richard Bacon, David James Neep +1 more | 2025-09-23 |
| 11884915 | Guide RNAs with chemical modification for prime editing | Daniel E. Ryan, Robert Kaiser | 2024-01-30 |
| 11851652 | Compositions comprising chemically modified guide RNAs for CRISPR/Cas-mediated editing of HBB | Matthew H. Porteus, Ayal Hendel, Joe Clark, Rasmus O. Bak, Daniel E. Ryan +2 more | 2023-12-26 |
| 11584773 | Phosphorous protecting groups and methods of preparation and use thereof | Luca Monfregola, Marvin H. Caruthers, Mithun Roy | 2023-02-21 |
| 11548876 | Orthoester compositions for affinity purification of oligonucleotides | Joel Myerson, Brian Phillip Smart | 2023-01-10 |
| 11535846 | Chemically modified guide RNAS for CRISPR/Cas-mediated gene regulation | Matthew H. Porteus, Ayal Hendel, Joe Clark, Rasmus O. Bak, Daniel E. Ryan +2 more | 2022-12-27 |
| 11306309 | Chemically modified guide RNAs for CRISPR/CAS-mediated gene regulation | Matthew H. Porteus, Ayal Hendel, Joe Clark, Rasmus O. Bak, Daniel E. Ryan +2 more | 2022-04-19 |
| 11299483 | Orthoester compositions for affinity purification of oligonucleotides | Joel Myerson, Brian Phillip Smart | 2022-04-12 |
| 11104699 | Phosphorous protecting groups and methods of preparation and use thereof | Luca Monfregola, Marvin H. Caruthers, Mithun Roy | 2021-08-31 |
| 10900034 | Guide RNA with chemical modifications | Daniel E. Ryan, Jeffrey R. Sampson, Robert Kaiser, Joel Myerson | 2021-01-26 |
| 10767175 | High specificity genome editing using chemically modified guide RNAs | Daniel E. Ryan, Subhadeep Roy, Jeffrey R. Sampson | 2020-09-08 |
| 10597421 | Protected monomer and method of final deprotection for RNA synthesis | Joel Myerson, Agnieszka Sierzchala, Geraldine F. Dellinger, Zoltan Timar | 2020-03-24 |
| 10337001 | Guide RNA with chemical modifications | Daniel E. Ryan, Jeffrey R. Sampson, Robert Kaiser, Joel Myerson | 2019-07-02 |
| 10196418 | Phosphorous protecting groups and methods of preparation and use thereof | Luca Monfregola, Marvin H. Caruthers, Mithun Roy | 2019-02-05 |
| 9896472 | Protected monomer and method of final deprotection for RNA synthesis | Joel Myerson, Agnieszka Sierzchala, Geraldine F. Dellinger, Zoltan Timar | 2018-02-20 |
| 9890190 | Preparation of long synthetic oligonucleotides by squarate conjugation chemistry | Kenneth W. Hill, Benjamin D. Lunstad | 2018-02-13 |
| 9802975 | Protecting groups for “Z nucleotide” and methods thereof | Benjamin D. Lunstad | 2017-10-31 |
| 9273086 | Protected monomer and method of final deprotection for RNA synthesis | Joel Myerson, Agnieszka Sierzchala, Geraldine F. Dellinger, Zoltan Timar | 2016-03-01 |
| 9169286 | Use of N-alkyl imidazole for sulfurization of oligonucleotides with an acetyl disulfide | Agnieszka Sierzchala, Paul Metz, Victor R Mokler | 2015-10-27 |
| 9067961 | Thiocarbon-protecting groups for RNA synthesis | Agnieszka Sierzchala, John Turner, Joel Myerson, Zoltan Kupihar, Fernando Ferreira +2 more | 2015-06-30 |
| 8846898 | Phosphinoamidite carboxylates and analogs thereof in the synthesis of oligonucleotide having reduced internucleotide charge | — | 2014-09-30 |
| 8642755 | Use of thioacetic acid derivatives in the sulfurization of oligonucleotides with phenylacetyl disulfide | Agnieszka Sierzchala, Victor R Mokler, Zoltan Timar | 2014-02-04 |
| 8552174 | Solutions, methods, and processes for deprotection of polynucleotides | Zoltan Timar, Agnieszka Sierzchala, Geraldine F. Dellinger, Marvin H. Caruthers, Joel Myerson | 2013-10-08 |
| 8309706 | Methods of synthesizing oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection | Marvin H. Caruthers, Jason Richard Betley | 2012-11-13 |
| 8309710 | Use of N-alkyl imidazole for sulfurization of oligonucleotides with an acetyl disulfide | Agnieszka Sierzchala, Paul Metz, Victor R Mokler | 2012-11-13 |